A unique opportunity is available for a candidate interested in working in a multidisciplinary environment applying advanced optical tools in biomedical research at the Center for Genomic Regulation (CRG)). The successful candidate will be expected to contribute to research in CellViewer FET open project, which is an H2020 European collaborative project. CellViewer focuses on elucidating nuclear architecture and how it regulates nuclear function. The successful candidate will use novel optical tools such as single particle tracking and super-resolution microscopy to resolve the dynamics and sub-cellular localization of nuclear architectural proteins and transcriptional machinery in cells undergoing differentiation. The long term goal would be to elucidate how molecular complexes coordinate their spatio-temporal organization to activate and repress genes during cell fate transitions. This project overall will give new insights into how cells determine their fate and therefore allow us to have better control over cell fate determination.
We are looking for highly motivated individuals with experience and background in the fields of microscopy, in particular single molecule tracking, image processing and statistical analysis.
Positively evaluated will be experience with optical methods, computer programming (Matlab, Python and similar) and a strong background in biophysics.
Deadline: Applications will be regularly reviewed until position is filled.
Maria Pia Cosma, PhD
Reprogramming and Regeneration
Center for Genomic Regulation (CRG)
Melike Lakadamyali, PhD
Perelman School of Medicine, Department of Physiology
University of Pennsylvania,
To apply for this position click here.